Answer
The answer is The Wire. Clarence Clemons, best known as the saxophonist for Bruce Springsteen's E Street Band, made a cameo appearance in the third season of the HBO drama series The Wire. He played a character named Clarence Royce, a jazz musician who mentors a young musician named Randy Wagstaff. Clemons' appearance was a nod to his own musical career and his friendship with The Wire creator David Simon.