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François Jacob, a distinguished French biologist and Nobel laureate, was born on June 17, 1920. His groundbreaking research, conducted in collaboration with Jacques Monod, elucidated the regulation of gene expression through the operon model, revolutionizing our understanding of genetic regulation and earning him the prestigious Nobel Prize in Physiology or Medicine in 1965. Jacob's contributions have profoundly influenced the field of molecular biology and continue to inspire scientific exploration.