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Roxie Hart, the protagonist in the musical "Chicago," is portrayed by Renée Zellweger. Roxie, an ambitious dancer, murders her unfaithful husband and subsequently becomes entangled in a web of deceit, celebrity, and corruption within Chicago's criminal justice system. Throughout the musical, Renée's portrayal of Roxie showcases her character's evolution, from a naïve dreamer to a cunning manipulator.