Answer
Crystallographic electron microscopy, pioneered by Aaron Klug, is a groundbreaking technique that merges the principles of crystallography and electron microscopy. By utilizing beams of electrons and analyzing the resulting diffraction patterns, this method enables the visualization of biological structures at the molecular level. Its significance lies in its ability to capture intricate details of complex biomolecules, such as proteins and viruses, without damaging or altering their delicate structures.