Answer
In the 1923 gubernatorial primary, Barkley narrowly lost to J. Campbell Cantrill. Cantrill, a prominent businessman and Democrat, emerged victorious amidst a competitive race. Despite Barkley's strong campaign, Cantrill's extensive political connections and wide recognition secured him the nomination. Factors such as Barkley's relative inexperience in state politics and his lack of established alliances are considered to have contributed to his defeat in the primary.