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What discovery did Martin Rodbell make in the 1960s that related to G proteins?

  • Their role in metabolism

  • Their absence in cancer cells

  • That GTP was involved in cell signaling

  • Their role in digestion

Answer

In the 1960s, Martin Rodbell discovered that guanosine triphosphate (GTP) played a crucial role in cell signaling. He identified the involvement of GTP in the activation and deactivation of certain proteins, known as G proteins, involved in transmitting signals within cells. This discovery provided a foundational understanding of how cells communicate and respond to external stimuli, paving the way for further advancements in the field of cell signaling and physiology.
Uncovering the Legacy of Alfred G. Gilman: A Pharmacologist Extraordinaire

Uncovering the Legacy of Alfred G. Gilman: A Pharmacologist Extraordinaire

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