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Awkwafina had a supporting role in the 2016 comedy film Neighbors 2: Sorority Rising. In the film, she plays the role of Shelby, a member of a sorority that moves in next door to the frat house that the main characters, Teddy and Pete, live in. Awkwafina's performance in the film was praised by critics, and she received a nomination for the MTV Movie Award for Best Breakthrough Performance.