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What does Tlr4 stand for in Bruce Beutler's research?

  • Transmission Light Reactor 4

  • Toll-Like Receptor 4

  • Total Liquid Relations 4

  • Tangent Levels Receptor 4

Answer

Toll-Like Receptor 4, or Tlr4, is a receptor on immune cells that recognizes a molecule called lipopolysaccharide (LPS). LPS is found on the surface of gram-negative bacteria, and when it binds to Tlr4, it triggers a cascade of events that leads to the activation of the immune system. This activation is necessary for fighting off infections caused by gram-negative bacteria.
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