What does'LPS-refractory' mean in regard to Bruce Beutler's research?
Resistant to the effects of lipopolysaccharide
Makes the lipopolysaccharide glow
Helps the body reduce fat
Strengthens the nervous system
Answer
Lipopolysaccharide (LPS) is a bacterial cell wall component that is toxic to human cells. In Beutler's research, LPS-refractory cells are cells that are resistant to the effects of LPS. This resistance is due to the presence of a protein called CD14, which binds to LPS and prevents it from entering the cell.
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