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"Sky High" marked Danielle Panabaker's debut in a Disney film, released in 2005. This superhero comedy-adventure tells the story of a high school for young heroes-in-training, where Panabaker plays the role of Layla Williams, a student with plant manipulation abilities. Alongside Michael Angarano and Kurt Russell, Panabaker's portrayal brings humor and relatability to a tale of self-discovery and navigating typical high school challenges amidst extraordinary circumstances.