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What did Fischer hypothesis concerning enzymes?

  • Catalyst theory

  • Lock and key mechanism

  • Protein denaturation

  • Enzyme inhibition

Answer

The Lock-and-Key Model, put forth by Emil Fischer, proposes that the active site of an enzyme exhibits a specific shape that perfectly accommodates and binds to the substrate molecule. This precise fit enables the enzyme to catalyze and enhance the rate of a specific biochemical reaction. The interaction between the enzyme and substrate resembles the way a key fits into its specific lock, illustrating their high degree of structural complementarity.
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