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In the 1990s, Euclid Tsakalotos became a member of Synaspismos, a political party aligned with the radical left in Greece. Synaspismos, meaning coalition in Greek, was formed when various left-wing and communist parties united in the late 1980s. Known for his economic expertise and leftist views, Tsakalotos played a significant role within Synaspismos, contributing to policy discussions and shaping the party's political stance on various economic issues.