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Anna Bolena, Donizetti's landmark opera, marked a turning point in his career, signaling his profound influence on the opera world. This serious opera premiered in 1830 and displayed Donizetti's mastery of dramatic storytelling, captivating melodies, and innovative use of vocal techniques. Anna Bolena set the stage for Donizetti's subsequent operatic triumphs and solidified his position as one of the leading composers of the bel canto era.