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In 2005, Heather Graham played the role of Mary, a troubled call girl in David Fincher's crime thriller "The Zodiac". The movie revolves around the real-life hunt for the infamous Zodiac serial killer, who terrorized California in the late 1960s and remained unidentified. Heather Graham's portrayal adds complexity to the narrative as her character's life intertwines with the investigation, shedding light on the social impact of the case.