Answer
Isla Fisher played the character Karen Gaffney in the 2016 film Keeping Up with the Joneses. Karen is the wife of Jeff Gaffney, played by Zach Galifianakis, and they are neighbours to the Joneses, a seemingly perfect family. When the Joneses move in, the Gaffneys are immediately drawn to their lifestyle and start trying to emulate them. However, they soon realise that the Joneses are not what they seem.