Answer
The movie in which Jodie Comer and Ryan Reynolds co-starred is "Free Guy." This 2021 science fiction action comedy film follows the story of Guy (Ryan Reynolds), a non-playable character in a video game who becomes self-aware and decides to take control of his own destiny. Jodie Comer portrays Millie Rusk, a programmer who works for the company that created the game and develops a relationship with Guy.