Answer
The iconic line, "Hello, Clarice," from "The Silence of the Lambs" is spoken by Hannibal Lecter, a brilliant but psychopathic cannibalistic serial killer, upon meeting Clarice Starling, a young and determined FBI trainee. The line sets the tone for their complex and chilling relationship, as Lecter manipulates and challenges Starling while she attempts to gain insight into his mind to solve a series of murders.