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What suppresses the immunogenicity of RNA, according to Katalin Karikó's co-discovery?

  • Nucleoside modifications

  • Protein alterations

  • DNA replication

  • Lipid functions

Answer

Katalin Karikó's co-discovery, nucleoside modifications, suppresses the immunogenicity of RNA. Nucleoside modifications, such as the addition of a methyl group to the 2' position of the ribose sugar, prevents the body's immune system from recognizing RNA as a foreign substance and attacking it. This allows RNA to be used safely in vaccines and other medical applications.
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