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Best Original Screenplay nominee Kumail Nanjiani co-wrote "The Big Sick" with his wife, Emily V. Gordon, based on their real-life courtship. The film follows the story of a Pakistani-American comedian (Nanjiani) who falls in love with a woman (Zoe Kazan) while she is in a medically induced coma. "The Big Sick" was a critical and commercial success, grossing over $40 million worldwide against a production budget of just $5 million.