Answer
Margaret of Anjou's parents were René, King of Naples, and Isabella, Duchess of Lorraine. Her father, René, was a member of the House of Anjou, a prominent noble family in France, while her mother, Isabella, was the daughter of Charles II, Duke of Lorraine. With this lineage, Margaret inherited royal blood and significant political connections, which would later shape her life and involvement in the political landscape of 15th-century Europe.