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Her daughter, Maria Sibylla Merian, took over as the family artist after Merian's death. She established herself as a renowned naturalist and artist, making significant contributions to the field of entomology through her detailed illustrations of insects and plants. Her work, particularly her book "Metamorphosis Insectorum Surinamensium," showcased her meticulous observations and artistic talent, solidifying her legacy as a pioneering female scientist and artist.