What does the "knockout" in knockout mice refer to?
Enhanced strength
A sleeping aid
Gene elimination
Immunity boost
Answer
The "knockout" in knockout mice refers to the targeted disruption or inactivation of a specific gene through genetic engineering. This technique allows researchers to study the function of genes by observing the effects of their absence in the organism. Knockout mice are created by replacing the functional gene with a modified version that does not produce a functional protein.
Unraveling Genes: The Mario Capecchi Nobel Quest
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