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The American Association for the Advancement of Science (AAAS) is a scientific organization founded in 1848 and headquartered in Washington, D.C. It is the largest general scientific society in the world, with more than 250,000 members. Its mission is to advance science, engineering, and innovation through collaboration with other organizations, and by acting on policy issues that affect the scientific enterprise. In 1972, Margaret Mead chaired the association.