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Oscar Isaac's first major role was as Joseph in The Nativity Story, a 2006 film directed by Catherine Hardwicke and starring Keisha Castle-Hughes. Isaac was 24 years old at the time and had previously appeared in a few small roles, including a minor part in the 2005 film The Life Aquatic with Steve Zissou. His performance in The Nativity Story was well-received by critics and helped to launch his career.