Answer
In the 18th century, Guanajuato in Mexico surpassed Potosí's silver production. Guanajuato's rich veins, innovative mining techniques, and abundant labor force contributed to its rise, while Potosí faced challenges such as flooding and declining ore quality. This shift marked a significant turning point in the global silver trade, with Guanajuato becoming one of the most important silver-producing regions in the world.