Was Ray Chapman's death the only instance of a player dying from an injury in a major league game?
Yes
No
Not documented
It's controversial
Answer
Yes, Ray Chapman's death is the only instance of a player dying from an injury in a major league game. The other three players who have died on the field died from heart attacks. Chapman was hit in the head by a pitch thrown by Carl Mays, and died a few hours later.
The Remarkable Ray Chapman: A Quiz on the Life and Legacy of an American Baseball Legend