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Ei-ichi Negishi, a Japanese chemist, shared the Nobel Prize in Chemistry with Richard Heck in 2010. Negishi's contributions focused on the development of palladium-catalyzed cross-coupling reactions, specifically the Negishi coupling, which involves the formation of carbon-carbon bonds between organic halides and organozinc reagents. This reaction has wide applications in organic synthesis, particularly in the pharmaceutical and agrochemical industries.