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In 2022, at the age of 82, Sidney Altman, a prominent Canadian-American molecular biologist, passed away. Remembered for his breakthrough research on the catalytic properties of RNA, Altman shared the Nobel Prize in Chemistry with Thomas Cech in 1989 for their discovery of ribozymes. His significant contributions advanced the comprehension of RNA's diverse roles beyond protein synthesis. Altman's legacy persists as a driving force within the field of molecular biology.