Answer
Tress MacNeille voiced Charlotte Pickles in the Nickelodeon animated series Rugrats. The series, which ran from 1991 to 2004, follows the adventures of a group of toddlers, including Tommy Pickles, Chuckie Finster, Phil and Lil DeVille, and Angelica Pickles. Charlotte Pickles is Tommy's grandmother and Angelica's mother. She is a kind and loving grandmother, but she can also be a bit overbearing at times.