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What is the Grignard reaction used to synthesize?

  • Acids

  • Alcohols

  • Proteins

  • Carbohydrates

Answer

Alcohols are the primary products of the Grignard reaction. This versatile reaction involves the nucleophilic addition of an organometallic Grignard reagent, formed by the reaction of an alkyl or aryl halide with magnesium metal, to a carbonyl group. The reaction proceeds via the formation of a tetrahedral intermediate, which upon protonation with an acidic workup, yields the corresponding alcohol.
Mastering the Mysterious Mind of Victor Grignard: A Chemist's Elixir of Knowledge

Mastering the Mysterious Mind of Victor Grignard: A Chemist's Elixir of Knowledge

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