Answer
No, Lopes did not manage in the Copa Libertadores. He spent his entire coaching career in Brazil, managing several clubs in the Campeonato Brasileiro Série A, including Grêmio, Internacional, and Palmeiras. He achieved notable success domestically, winning multiple state championships and the Brazilian Série A title with Grêmio in 1996. However, he never had the opportunity to manage in the Copa Libertadores, which is South America's premier club competition.