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The second wife of Charles Stewart, 3rd Marquess of Londonderry, was Lady Frances Anne Vane, daughter of the 1st Marquess of Londonderry and his first wife, Lady Mary FitzGerald. Born in 1755, she wed Londonderry in 1775, and they enjoyed a happy marriage until her passing in 1788. She is remembered for her elegance, artistic talent, and philanthropy, actively supporting charitable causes and artistic endeavors within Londonderry's circle.