What element is central to Negishi coupling?
Palladium
Gold
Silver
Platinum
Answer
Palladium is the central element in Negishi coupling, a cross-coupling reaction in organic chemistry. It involves the coupling of an organozinc reagent with an organic halide, catalyzed by a palladium complex. The reaction is widely used in the synthesis of complex organic molecules, including natural products and pharmaceuticals. Palladium's ability to activate both the organozinc and organic halide reagents makes it essential for the success of the reaction.
Ei-ichi Negishi: A Comprehensive Quiz for True Experts
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