Answer
Negishi coupling, named after Ei-ichi Negishi, is a palladium-catalyzed cross-coupling reaction that forms carbon-carbon bonds between organic halides and organozinc reagents. This versatile reaction has revolutionized organic synthesis, enabling the construction of complex organic molecules with high efficiency and selectivity. Negishi coupling is widely used in the pharmaceutical, agrochemical, and materials industries, and has played a significant role in the development of new drugs, pesticides, and advanced materials.