What is the Negishi coupling used for?
Organic synthesis
DNA replication
Protein synthesis
Quantum computing
Answer
The Negishi coupling is a versatile carbon-carbon bond-forming reaction used in organic synthesis. It involves the coupling of an organozinc reagent with an organic halide or triflate, catalyzed by a palladium complex. This reaction allows for the formation of various carbon-carbon bonds, including aryl-aryl, aryl-alkyl, and alkyl-alkyl bonds, making it a valuable tool for the construction of complex organic molecules.
Ei-ichi Negishi: A Comprehensive Quiz for True Experts
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