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Japanese chemist Ei-ichi Negishi was born in 1935 in Changchun, China, to Japanese parents. He is best known for his work in organic chemistry, particularly for the development of the Negishi coupling reaction, which is used to form carbon-carbon bonds. Negishi shared the 2010 Nobel Prize in Chemistry with Richard F. Heck and Akira Suzuki for their work on palladium-catalyzed cross couplings in organic synthesis.