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What was proven through Beadle and Tatum's experiment?

  • All species share DNA

  • Genes control metabolism

  • Proteins don't affect genes

  • Cells work independently of genes

Answer

Indeed, genes control metabolism. This was elegantly demonstrated by George Beadle and Edward Tatum in their groundbreaking experiments with the fungus Neurospora crassa. They irradiated Neurospora spores with X-rays to induce mutations and screened for mutants unable to synthesize specific nutrients. By correlating specific mutations with the inability to produce specific metabolites, they established a direct link between genes and the enzymes that control metabolic pathways.
Unraveling the Genetic Legacy: The George Beadle Quiz

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