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"One Flew Over the Cuckoo's Nest," directed by Miloš Forman, earned him his first Academy Award for Best Director. The 1975 American drama, based on Ken Kesey's 1962 novel, tells the story of Randle Patrick McMurphy (Jack Nicholson), a rebellious patient who arrives at a mental hospital and clashes with the oppressive Nurse Ratched (Louise Fletcher).