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"Twist of Fate" is the second single released from Siobhán Donaghy's debut solo album, "Revolution in Me." The song showcases Donaghy's signature blend of pop and R&B influences, with introspective lyrics that explore themes of love, loss, and self-discovery. It was a commercial success, reaching the top 20 in the UK Singles Chart and solidifying Donaghy's status as a rising star in the music industry.