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Rosie Perez featured in the 2020 TV series The Flight Attendant. Perez plays the role of Megan Briscoe, a friend of the protagonist Cassie Bowden. The series follows Bowden as she tries to piece together her life after a night of drinking results in her waking up next to a dead man. The Flight Attendant was a critical and commercial success, and Perez received praise for her performance.