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Statesville is a city in North Carolina, United States. It is the county seat of Iredell County and the 16th largest city in North Carolina. Statesville was founded in 1789 and incorporated in 1819. The city is located in the Piedmont region of North Carolina and is situated along the Yadkin River. Statesville has a population of over 26,000 people and is home to a variety of businesses and industries.