Answer
The answer is no, Alexandre Lacazette never managed to achieve this feat throughout his time playing in Ligue 1. Despite being a prolific goal scorer, he faced tough competition from players like Edinson Cavani, Zlatan Ibrahimović, Radamel Falcao, Kylian Mbappé and more recently Wissam Ben Yedder, eventually preventing him from ever securing the title of top goalscorer in the league.