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The Duomo, with its magnificent white and pink marble facade, dominates Urbino's skyline and is a masterpiece of Renaissance architecture. Designed by Francesco di Giorgio Martini and Luciano Laurana, its construction began in the 15th century and blended elements of Gothic and Renaissance styles. The interior boasts stunning frescoes by Federico Barocci and exquisite carvings, making it a must-see attraction for visitors to this charming Italian city.