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In 2006, Virginia Madsen graced the silver screen in Robert Altman's heartwarming comedy-drama "A Prairie Home Companion." The film follows the final broadcast of a beloved radio show, featuring an ensemble cast including Garrison Keillor, Meryl Streep, and Lily Tomlin. Madsen's portrayal of Yolanda Johnson, a shy and insecure singer, adds a touch of vulnerability and charm to the ensemble.