Answer
Renteria hit game-winning home runs in the 2010 World Series twice. In the sixth inning of Game 2, with the score tied 1-1, he hit a two-run home run off of Phillies pitcher Cole Hamels. In the ninth inning of Game 4, with the score tied 4-4, he hit a walk-off home run off of Phillies closer Brad Lidge. These two home runs helped the Giants win the World Series.